反应详情

[2-(3,4-dichloro-phenyl)-ethyl]-(2,2-difluoro-benzo[1,3]dioxol-5-ylmethyl)-amine was synthesized in analogy to the above procedure using 100 mg of 2,2-difluoro-1,3-benzodioxole-5-carbaldehyde (0.54 mmol), 102 mg of 2-(3,4-dichloro-phenyl)-ethylamine (0.54 mmol) and 31 mg of sodium borohydride (0.81 mmol). The isolated colorless semisolid (98 mg, 51%) was used in the following step without further purification. MS (ISP) 360.0 (M+H)+.

1. customThe isolated colorless semisolid (98 mg, 51%) was used in the following step without further purification