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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 855319Generated: October 29, 2026

3,4-Dichlorophenethylamine → HCID 69343082, compound

https://huagongshe.com/reaction/855319

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DichlorophenethylamineHCID 217958—
ReactantSodium borohydrideHCID 4311764—
ReactantHCID 22259691HCID 22259691—
Reactant(4-Cyclopropylbenzyl)-[2-(4-fluoro-3-trifluoromethylphenyl)-ethyl]-amineHCID 69342889—
ProductHCID 69343082HCID 6934308286%

Reaction Steps

The title compound was synthesized in analogy to (4-cyclopropylbenzyl)-[2-(4-fluoro-3-trifluoromethylphenyl)-ethyl]-amine (described in example S53) using 4-tert-butyl-3-chloro-benzaldehyde (prepared as described in example S110) (72 mg, 0.37 mmol), 2-(3,4-dichlorophenyl)-ethylamine (70 mg, 0.37 mmol) and sodium borohydride (21 mg, 0.55 mmol). The desired product (117 mg, 86%) was isolated without further purification as a colorless oil. MS (ISP) 370.1 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07259183B2
Source datasetuspto-grants-2007_08
ORD IDord-c96bdc3349e94deeb040e655d8bd76ee
Source noteuspto-grants-2007_08