HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dichlorophenethylamine → HCID 69343082, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dichlorophenethylamine | HCID 217958 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 22259691 | HCID 22259691 | — |
| Reactant | (4-Cyclopropylbenzyl)-[2-(4-fluoro-3-trifluoromethylphenyl)-ethyl]-amine | HCID 69342889 | — |
| Product | HCID 69343082 | HCID 69343082 | 86% |
Reaction Steps
The title compound was synthesized in analogy to (4-cyclopropylbenzyl)-[2-(4-fluoro-3-trifluoromethylphenyl)-ethyl]-amine (described in example S53) using 4-tert-butyl-3-chloro-benzaldehyde (prepared as described in example S110) (72 mg, 0.37 mmol), 2-(3,4-dichlorophenyl)-ethylamine (70 mg, 0.37 mmol) and sodium borohydride (21 mg, 0.55 mmol). The desired product (117 mg, 86%) was isolated without further purification as a colorless oil. MS (ISP) 370.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07259183B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-c96bdc3349e94deeb040e655d8bd76ee |
| Source note | uspto-grants-2007_08 |