3,4-Dichlorophenethylamine → [3-Chloro-4-(1-methoxy-1-methyl-ethyl)-benzyl]-[2-(3,4-dichloro-phenyl)-ethyl]-amine

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Reaction Steps

The title compound was synthesized in analogy to (4-cyclopropylbenzyl)-[2-(4-fluoro-3-trifluoromethylphenyl)-ethyl]-amine (described in example S53) using 77 mg of 3-chloro-4-(1-methoxy-1-methyl-ethyl)-benzaldehyde (0.36 mmol) (described in example S117), 69 mg of 2-(3,4-dichloro-phenyl)-ethylamine (0.36 mmol) and 21 mg of sodium borohydride (0.54 mmol). The isolated colorless liquid (126 mg, 90%) was used in the following step without further purification. MS (ISP) 386.1 (M+H)+.

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