反应详情

268 mg (1 mmol) of (4-tert-butyl-benzyl)-(2-pyridin-4-yl-ethyl)-amine, 196 mg (1 mmol) of 5-chloro-1H-indole-7-carboxylic acid and 217 mg (1.1 mmol) of EDC.HCl were stirred over night at rt in 20 ml DCM. The product was purified by column chromatography (silica gel; EtOAc) to yield 210 mg (47%) product as a colorless oil. MS (ISP) 446.0 (M+H)+.

1. customThe product was purified by column chromatography (silica gel; EtOAc)