1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride → HCID 69513555, compound

Participants

Reaction Steps

65 mg (0.33 mol) of 5-chloro-1H-indol-7-carboxylic acid, 89 mg (0.30 mmol) of [rac]-(4-tert-butyl-benzyl)-(3-furan-2-yl-butyl)-amine and 63 mg (0.33 mmol) of EDC.HCl were dissolved in 3 ml DCM. The reaction mixture was stirred at rt over night. The solvent was evaporated and the residue was purified by column chromatography (20 g silica gel, heptane/EtOAc 4:1) to yield 94 mg (66%) product as a colorless viscous oil. MS (ISP) 477.2 (M+H)+.

Provenance & Evidence