Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) → HCID 69492200, compound

Participants

Reaction Conditions

Reaction Steps

6.4 g of (R)-4-(4-(6-Acryloyloxyhexyloxy)benzoyloxy)cinnamic acid 2-(tetrahydropyran-2-yloxy)-2-phenyl-ethyl ester (20) (9.8 mmole) were dissolved in 35 ml of absolute ethanol and 0.5 g (2 mmole) of pyridinium 4-toluensulfonate and 40 mg of 4-methoxyphenol (to avoid polymerization) were added. The mixture was heated at 55° C. for 20 h. After cooling to room temperature, a white powder precipitated. It was filtered and washed with ethanol. It was dried in a dessicator with silica. 3 g of a white solid (55%) were obtained.

Provenance & Evidence