Triethylamine → 7-methoxy-4H-1,2,4-benzothiadiazine 1,1-dioxide

Participants

Reaction Conditions

Reaction Steps

There is stirred for 1 night at 80° C. a suspension of 3.0 g of 2-amino-5-methoxybenzene-sulphonamide in the presence of 1.31 g of formamidine hydrochloride and 2.27 ml of triethylamine in 50 ml of toluene. The toluene is evaporated off in vacuo. The residue is taken up in water and the precipitate is filtered off.

Provenance & Evidence