HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 855790Generated: October 29, 2026
2-(Trifluoromethyl)phenyl isocyanate → HCID 86592175, compound
https://huagongshe.com/reaction/855790
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-(Trifluoromethyl)phenyl isocyanate | HCID 16794 | — |
| Reactant | HCID 68806941 | HCID 68806941 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 86592175 | HCID 86592175 | 11% |
Reaction Steps
100 mg (0.24 mmol) of methyl 3-{4-amino-2-[3-(2-chloro-4,5-difluorobenzoyl)-ureido]phenyl}acrylate were dissolved in 1 ml of acetonitrile and mixed with 2-trifluoromethylphenyl isocyanate and shaken at 60° C. for 14 hours. The resulting precipitate was filtered off with suction, and 16 mg (11%) of the desired product were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07262220B2 |
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| Source dataset | uspto-grants-2007_08 |
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| ORD ID | ord-cf1f629a5040471ca631c9a2fe690c0b |
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| Source note | uspto-grants-2007_08 |
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