2-Methylbenzoic acid → 5-(Chlorosulfonyl)-2-methylbenzoic acid

Participants

Reaction Conditions

Reaction Steps

A mixture of o-toluic acid (15 g, 0.11 mol) and chlorosulfonic acid (30 ml) was heated at 100° C. under nitrogen for 2.5 h. The reaction mixture was then poured onto ice (500 ml) and the resulting precipitate was filtered, yielding the title compound as an off-white solid (20 g, 78% yield). MP 151–155° C.

Provenance & Evidence