HCID 13591070, compound → HCID 69481685, compound

HRID 856201Notes

Reaction equation

HRID 856201 reaction equation
Cl[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)N(C(Cl)=O)[CH2:6][CH2:5]2.ClC1C=C2[C:21](=[CH:22][CH:23]=1)[CH2:20][N:19]([C:24](Cl)=O)C2.ClC1C=C2C(=CC=1)CN([C:38](Cl)=[O:39])CC2.[Cl:41]C1C=C2C(=CC=1)N(C(Cl)=O)CCC2>>[Cl:41][C:10]1[CH:2]=[CH:3][C:4]([CH:5]=[CH:6][CH2:38][O:39][CH:22]2[CH2:21][CH2:20][NH:19][CH2:24][CH2:23]2)=[CH:8][CH:9]=1

Participants

5

Reactant 4

HCID 13591070HCID 13591070, compoundHCID 23081405HCID 23081405, compoundHCID 23081514HCID 23081514, compoundHCID 23081549HCID 23081549, compound

Product 1

HCID 69481685HCID 69481685, compound

Procedure

Using 5-chloro-2,3-dihydroindole-1-carbonylchloride, 5-chloro-1,3-dihydroisoindol-2-carbonylchloride, 6-chloro-3,4-dihydro-1H-isoquinoline-2-carbonylchloride or 6-chloro-3,4-dihydro-2H-quinoline-1-carbonylchloride gave compounds of Examples 113 to 116 in the same manner as in Example 106.

Sources & evidence

ORD record
ord-a67fbf4f94a247c3a2196e61bc9df826
Source dataset
uspto-grants-2007_08
Patent number
US07262212B2

Reaction notes

Loading…