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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 856263Generated: October 28, 2026

(R)-2-chloro-1-(2-methyloxiran-2-ylmethyl)-4-nitroimidazole → HCID 69480112, compound

https://huagongshe.com/reaction/856263

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-2-chloro-1-(2-methyloxiran-2-ylmethyl)-4-nitroimidazoleHCID 10443353—
ReactantHCID 23081575HCID 23081575—
ProductHCID 69480112HCID 69480112—

Reaction Steps

Using 4-(4-trifluoromethoxybenzyl)piperidine and (R)-2-chloro-1-(2-methyloxiran-2-ylmethyl)-4-nitroimidazole prepared in Example 12 gave (S)-1-(2-chloro-4-nitroimidazol-1-yl)-2-methyl-3-[4-(4-trifluoromethoxybenzyl)piperidin-1-yl]propan-2-ol (crude) as a yellow oil in the same manner as in Example 270.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07262212B2
Source datasetuspto-grants-2007_08
ORD IDord-8c644582b67247858e2850fd7bec1f39
Source noteuspto-grants-2007_08