HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(N-Boc-amino)piperidine → HCID 86760532, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(N-Boc-amino)piperidine | HCID 723833 | — |
| Reactant | (R)-2-chloro-1-(2-methyloxiran-2-ylmethyl)-4-nitroimidazole | HCID 10443353 | — |
| Product | HCID 86760532 | HCID 86760532 | 92% |
Reaction Steps
Using (R)-2-chloro-1-(2-methyloxiran-2-yl-methyl)-4-nitroimidazole prepared in Example 12 and tert-butyl piperidin-4-ylcarbamate gave tert-butyl (S)-{1-[3-(2-chloro-4-nitroimidazol-1-yl)-2-hydroxy-2-methylpropyl]piperidin-4-yl}carbamate (yield 92%) a yellow oil in the same manner as in Example 277.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07262212B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-f1f07022b1534d0c83d611244a94cc08 |
| Source note | uspto-grants-2007_08 |