Calcium Chloride → HCID 86595194, compound

Participants

Reaction Steps

4-nitrophenyl 2-(4-propyl-4H-1,2,4-triazol-3-yl)ethylsulfide (3.2 g), reduced iron (3.1 g) and calcium chloride (0.6 g) were added to 85% aqueous solution of ethanol (100 ml), and the mixture was refluxed for 3 hours. The reaction solution was filtered with Celite, and the solvent of the filtrate was distilled off. The residue was purified by silica gel column chromatography (elution solvent: triethylamine/methanol/ethyl acetate), to give 4-aminophenyl 2-(4-propyl-4H-1,2,4-triazol-3-yl)ethylsulfide (3.0 g) as yellow amorphous.

Provenance & Evidence