Calcium Chloride → HCID 69522088, compound

Participants

Reaction Steps

1-nitro-4-[(4-propyl-1H-1,2,4-triazole-5-one-3-yl)methylthio]benzene (0.5 g), reduced iron (0.5 g) and calcium chloride (0.1 g) were added to 85% aqueous solution of ethanol (15 ml), and the mixture was refluxed for 2 hours. The reaction solution was filtered with. Celite, and the solvent of the filtrate was distilled off. The residue was purified by basic silica gel column chromatography (elution solvent: ethyl acetate) to give 4-[(4-propyl-1H-1,2,4-triazole-5-one-3-yl)methylthio]aniline (0.4 g) as pale brown crystals.

Provenance & Evidence