Calcium Chloride → HCID 69522585, compound

Participants

Reaction Steps

A mixture of 4-[2-(4-nitrophenylthio)ethyl]-4H-1,2,4-triazole (1.0 g), reduced iron (1.12 g) and calcium chloride (0.22 g) in 15% hydrous ethanol (30 ml) was heated to reflux for 22 hours. The reaction mixture was concentrated under reduced pressure, and the obtained residue was separated and purified by column chromatography (basic silica gel, ethanol:ethyl acetate.: 1:19→1:9), to give 4-[2-(4-aminophenylthio)ethyl]-4H-1,2,4-triazole (0.79 g) as colorless crystals.

Provenance & Evidence