反应详情

To a solution of N-methyl-N-(4-nitrobenzyl)trifluoroacetoamide (11.82 g) in methanol (200 ml) was added 1N aqueous solution of sodium hydroxide (50 ml) at room temperature. The mixture was stirred at room temperature for 24 hours, and concentrated under reduced pressure. The mixture was extracted with ethyl acetate and dried over magnesium sulfate. The mixture was concentrated under reduced pressure, to give methyl(4-nitrobenzyl)amine (6.78 g).

1. concentrationconcentrated under reduced pressure
2. extractionThe mixture was extracted with ethyl acetate
3. dry with materialdried over magnesium sulfate
4. concentrationThe mixture was concentrated under reduced pressure