HCID 69521228, compound → HCID 69522409, compound

Participants

Reaction Steps

To 3-[[[4-nitro-2-(trifluoromethyl)phenyl]sulfanyl]methyl]pyridine (2.2 g) was added acetic acid (22 ml), and reduced iron (6.6 g) was added to the mixture, and the mixture was stirred for 240 hours at room temperature. The mixture was filtered with Celite, and the mixture was washed with ethyl acetate. The solvent was removed under reduced pressure, and the obtained residue was purified by silica gel column chromatography, to give 4-[(3-pyridinylmethyl)sulfanyl]-3-(trifluoromethyl)aniline (0.83 g).

Provenance & Evidence