反应详情

To 2-methoxy-4-nitrobenzenethiol (7.0 g) was added acetic acid (70 ml), reduced iron (21 g) was added to the mixture, and the mixture was stirred for 6 hours at room temperature. The mixture was filtered with Celite, and washed with ethyl acetate. The solvent was removed under reduced pressure, and the obtained residue was purified by silica gel column chromatography, to give 4-amino-2-methoxybenzenethiol (3.1 g).

1. additionwas added to the mixture
2. filtrationThe mixture was filtered with Celite
3. washwashed with ethyl acetate
4. customThe solvent was removed under reduced pressure
5. customthe obtained residue was purified by silica gel column chromatography