Iodoethane → HCID 69522449, compound

Participants

Reaction Conditions

Reaction Steps

To 5-[[(4-nitrophenyl)sulfanyl]methyl]-1,2,3,4-tetrazole (4.1 g) was added acetonitrile (203 ml), potassium carbonate (7.1 g) and iodoethane (3.3 ml) were added to the mixture, and the mixture was stirred for 140 hours at 50° C. The solvent was removed under reduced pressure, and to the obtained residue was added ethyl acetate, and the mixture was washed with water and saturated brine, and dried over magnesium sulfate. The solvent was removed under reduced pressure and the obtained residue was washed with hexane/ethyl acetate, to give 1-ethyl-5-[[(4-nitrophenyl)sulfanyl]methyl]-1,2,3,4-tetrazole and 2-ethyl-5-[[(4-nitrophenyl)sulfanyl]methyl]-1,2,3,4-tetrazole as mixture (4.2 g).

Provenance & Evidence