反应详情

To 2-chloro-4-nitrobenzenethiol (4.0 g) was added acetic acid (60 ml), and to this solution was added reduced iron (21 g), and the mixture was stirred at room temperature for 3 hours. The mixture was filtered with Celite, and washed with ethyl acetate. The solvent was removed under reduced pressure, and the obtained residue was purified by silica gel column chromatography, to give 4-amino-2-chlorobenzenethiol (2.74 g).

1. filtrationThe mixture was filtered with Celite
2. washwashed with ethyl acetate
3. customThe solvent was removed under reduced pressure
4. customthe obtained residue was purified by silica gel column chromatography