Thionyl Chloride → HCID 22938559, compound

HRID 856755Notes

Reaction equation

HRID 856755 reaction equation
[CH2:1]([N:5]1[CH:9]=[CH:8][N:7]=[C:6]1[CH2:10]O)[CH2:2][CH2:3][CH3:4].S(Cl)([Cl:14])=O>>[ClH:14].[CH2:1]([N:5]1[CH:9]=[CH:8][N:7]=[C:6]1[CH2:10][Cl:14])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 579275HCID 579275, compound

Product 1

HCID 22938559HCID 22938559, compound

Conditions

Temperature
90 °C

Procedure

To 1-butyl-2-hydroxymethylimidazole (3.0 g) was added thionyl chloride (30 ml), and the mixture was heated for 30 minutes under nitrogen atmosphere at 90° C. The mixture was allowed to be at room temperature, the solvent was distilled off under reduced pressure, and the obtained solid was washed with ethyl acetate, to give 1-butyl-2-chloromethylimidazole hydrochloride (3.5 g) as brown crystals.

Workup

  1. customto be at room temperature
  2. distillationthe solvent was distilled off under reduced pressure
  3. washthe obtained solid was washed with ethyl acetate

Sources & evidence

ORD record
ord-378de7c45d62471a8e0fc44ab0792e6d
Source dataset
uspto-grants-2007_08
Patent number
US07262185B2

Reaction notes

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