Acrolein → HCID 21862829, compound

HRID 856813Notes

Reaction equation

HRID 856813 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([S:18](=[O:21])(=[O:20])[NH2:19])=[CH:14][CH:13]=2)[C:9]#N)=[CH:4][CH:3]=1.[CH:22]([CH:24]=C)=O>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:11]([C:12]3[CH:17]=[CH:16][C:15]([S:18](=[O:21])(=[O:20])[NH2:19])=[CH:14][CH:13]=3)[CH:22]=[CH:24][CH:9]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7847AcroleinHCID 21862809HCID 21862809, compound

Product 1

HCID 21862829HCID 21862829, compound

Procedure

Following a procedure similar to that described in Example 1(iii), but using α-(4-methylphenyl)-α-(4-sulfamoylanilino)acetonitrile [prepared as described in step (ii) above] and acrolein as starting materials, the title compound was obtained as a brown powder (yield 13%), melting at 183-184° C.

Sources & evidence

ORD record
ord-fcbdbaec14734beb8ea06418f985b35f
Source dataset
uspto-grants-2006_12
Patent number
USRE039420E1

Reaction notes

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