反应详情

温度

20 °C

A solution of 3-iodoaniline (9.39 g) in dichloromethane (75 ml) was treated with ethyl isocyanatoacetate (7.21 ml) at 0° C. and the mixture was stirred for 2 h and allowed to warm to 20° C. EtOH (10 ml) was added and the mixture was stirred for 15 h. The solvents were evaporated under reduced pressure and the residue was triturated in Et2O to give the title compound (12.9 g)LCMS RT=3.08 min.

1. stirringthe mixture was stirred for 15 h
2. customThe solvents were evaporated under reduced pressure
3. customthe residue was triturated in Et2O