HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 857123Generated: November 1, 2026
Aminoacetaldehyde dimethyl acetal → N-(2,2-Dimethoxyethyl)-N'-(3-iodophenyl)urea
https://huagongshe.com/reaction/857123
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Aminoacetaldehyde dimethyl acetal | HCID 89728 | — |
| Reactant | 1-Iodo-3-isocyanatobenzene | HCID 4499000 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-(2,2-Dimethoxyethyl)-N'-(3-iodophenyl)urea | HCID 21867194 | — |
Reaction Steps
A suspension of 3-iodophenylisocyanate (1.1 g) in DCM (10 ml) was treated with aminoacetaldehyde dimethyl acetal (0.49 ml) and stirred under nitrogen at 20° C. for 24 h. The reaction mixture was quenched by adding MeOH. The solvents were removed under reduced pressure to give the title compound (1.35 g) LCMS RT=2.92 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07144908B2 |
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| Source dataset | uspto-grants-2006_12 |
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| ORD ID | ord-05b5adbcf5534c8fbac6b3df4bc730fc |
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| Source note | uspto-grants-2006_12 |
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