HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-aminocinnamate → Methyl 3-(3-aminophenyl)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-aminocinnamate | HCID 54385173 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Methyl 3-(3-aminophenyl)propanoate | HCID 10442275 | 98.9% |
Reaction Steps
A mixture of 3-(3-amino-phenyl)-acrylic acid methyl ester (6 g) and 10% Pd on activated carbon (1 g) in ethanol (50 ml) was hydrogenated at 30 psi for 18 h and filtered over Celite. Removal of the volatiles in vacuo provided 3-(3-amino-phenyl)propionic acid methyl ester (6 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07144911B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-9fd44232cf664ad19ad9a8bf2457ce1f |
| Source note | uspto-grants-2006_12 |