Iodide Ion → HCID 21867266, compound

Participants

Reaction Steps

Methyl[3,5-dibromo-4-(4-methoxyphenoxy)phenyl]acetate (1.0 g, 2.3 mmol), silver (I) sulfate (1.6 g, 4.6 mmol) and methanol (10 mL) was stirred in the dark at −78° C. Iodide (1.2 g, 4.6 mmol) was added and the reaction mixture was allowed to reach room temperature after 10 minutes. The yellow precipitate was filtered off, the eluate dissolved in ethyl actetate and washed with water. After concentration of the organic phase, 0.82 g (64%) of methyl [3,5-dibromo-4-(4-methoxy-3-iodophenoxy)phenyl]acetate was obtained.

Provenance & Evidence