HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dibromoethane → 4-(2-Bromoethoxy)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dibromoethane | HCID 7839 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Cyanophenol | HCID 13019 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 4-(2-Bromoethoxy)benzonitrile | HCID 2452212 | 45% |
Reaction Steps
A mixture of 4-cyanophenol (35.7 g, 0.3 mol), K2CO3 (41.4 g, 0.3 mol) and 1,2-dibromoethane (561 g, 3.0 mol) in MeCN (450 mL) was stirred under reflux overnight. The mixture was filtered and evaporated to give 30.2 g (45%) of the sub-title compound, which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07144914B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-f358b5afc1fd49d280237c0e65ff4731 |
| Source note | uspto-grants-2006_12 |