N-bromobutanimide → HCID 21867385, compound

Participants

Reaction Steps

To a solution of 2 g of 3-(4-chlorobenzyl)-1H-indole in 50 mL of CCl4 was added 1.8 g of NBS. The reaction mixture was stirred for 1 hour at room temperature and diluted with 50 mL of 5:1 hexane/EtOAc. The mixture was then filtered through a pad of silica gel and the filtrate was concentrated under reduced pressure to give the crude title compound, which was used for the next step without further purification.

Provenance & Evidence