Tributylphenyltin → HCID 58760722, compound

HRID 857390Notes

Reaction equation

C[CH:2]([CH:6]1[C:10]2=[C:11]([S:25][C:26]3[CH:31]=[CH:30][C:29]([Cl:32])=[CH:28][CH:27]=3)[C:12]3[C:13](Br)=[CH:14][C:15]([C:18]4[N:19]=[N:20][N:21]([CH3:23])[N:22]=4)=[CH:16][C:17]=3[N:9]2[CH2:8][CH2:7]1)[C:3]([O-:5])=[O:4].C([Sn](CCCC)(CCCC)[C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1)CCC>>[Cl:32][C:29]1[CH:28]=[CH:27][C:26]([S:25][C:11]2[C:12]3[C:13]([C:38]4[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=4)=[CH:14][C:15]([C:18]4[N:19]=[N:20][N:21]([CH3:23])[N:22]=4)=[CH:16][C:17]=3[N:9]3[CH2:8][CH2:7][CH:6]([CH2:2][C:3]([OH:5])=[O:4])[C:10]=23)=[CH:31][CH:30]=1

Participants

Reactant 2

HCID 607632Tributylphenyltin

HCID 86760310HCID 86760310, compound

Product 1

HCID 58760722HCID 58760722, compound

Procedure

Starting from (+/−)-methyl[8-bromo-9-[(4-chlorophenyl)thio]-6-(2-methyl-2H-tetrazol-5-yl)-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl]acetate and tributyl(phenyl)stannane, the title compound was synthesized by following the procedures described in Example 42 and Step 10 of Example 7.

Sources & evidence

ORD record: ord-550cd5e5e65a4534a4250ba07a8e29e4
Source dataset: uspto-grants-2006_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07144913B2

Reaction notes

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