Benzoyl chloride, 3,4-dichloro- → HCID 58760769, compound

HRID 857420Notes

Reaction equation

HRID 857420 reaction equation
C[CH:2]([CH:6]1[C:10]2=[CH:11][C:12]3[C:13]([CH:19]([CH3:21])[CH3:20])=[CH:14][C:15]([F:18])=[CH:16][C:17]=3[N:9]2[CH2:8][CH2:7]1)[C:3]([O-:5])=[O:4].[Cl:22][C:23]1[CH:24]=[C:25]([CH:29]=[CH:30][C:31]=1[Cl:32])[C:26](Cl)=[O:27]>>[Cl:22][C:23]1[CH:24]=[C:25]([CH:29]=[CH:30][C:31]=1[Cl:32])[C:26]([C:11]1[C:12]2[C:13]([CH:19]([CH3:20])[CH3:21])=[CH:14][C:15]([F:18])=[CH:16][C:17]=2[N:9]2[CH2:8][CH2:7][CH:6]([CH2:2][C:3]([OH:5])=[O:4])[C:10]=12)=[O:27]

Participants

3

Reactant 2

HCID 76403Benzoyl chloride, 3,4-dichloro-HCID 21867413HCID 21867413, compound

Product 1

HCID 58760769HCID 58760769, compound

Procedure

Starting from methyl(6-fluoro-8-isopropyl-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate (Example 44, Step 2) and 3,4-dichlorobenzoyl chloride, the title compound was synthesized following the procedures described in Step 1 of Example 61 and Step 10 of Example 7.

Sources & evidence

ORD record
ord-020a51fd094e4af0abe5a7b692091c58
Source dataset
uspto-grants-2006_12
Patent number
US07144913B2

Reaction notes

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