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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 857670생성일: 2026년 10월 25일

tert-Butyl 4-formylpiperidine-1-carboxylate → 4-({2-[6-(2-Acetylamino-benzothiazol-4-yloxy)-pyrimidin-4-yl]-5-trifluoromethyl-phenylamino}-methyl)-piperidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/857670

반응식

참여 물질

역할이름HCID투입량
반응물tert-Butyl 4-formylpiperidine-1-carboxylateHCID 1514430—
반응물N-(4-(6-(2-Amino-4-(trifluoromethyl)phenyl)pyrimidin-4-yloxy)benzo[d]thiazol-2-yl)acetamideHCID 21865046—
생성물4-({2-[6-(2-Acetylamino-benzothiazol-4-yloxy)-pyrimidin-4-yl]-5-trifluoromethyl-phenylamino}-methyl)-piperidine-1-carboxylic acid tert-butyl esterHCID 21865131—

반응 단계

The title compound was prepared from N-{4-[6-(2-amino-4-trifluoromethyl-phenyl)-pyrimidin-4-yloxy]-benzothiazol-2-yl}-acetamide (Example 151) and N-Boc-4-piperidinylcarboxaldehyde according the procedure described in Example 159. MS(ESI, pos. ion) m/z: 643 (M+1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07144888B2
출처 데이터셋uspto-grants-2006_12
ORD IDord-ff5aaa95da364177a2839aa5230f0e80
출처 메모uspto-grants-2006_12