Hydrochloric Acid → HCID 69655848, compound

Participants

Reaction Steps

The polar isomer of tert-butyl 1-[(3-chlorophenyl)(hydroxy)pyridin-3-ylacetyl]-L-prolinate (0.059 g, 0.14 mmol) was dissolved in THF (1 mL) and 6N hydrochloric acid (2 mL) and stirred for 24 hours at room temperature. The mixture was then evaporated in vacuo and vacuum dried to yield the polar isomer of 1-[(3-chlorophenyl)(hydroxy)pyridin-3-ylacetyl]-L-proline (0.051 g, HPLC RT=2.399 min, Method A; LCMS m/z=361).

Provenance & Evidence