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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 857776Generated: October 29, 2026

1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)- → N-[5-fluoro-2-(1H-tetraazol-1-yl)benzyl]-L-prolinamide

https://huagongshe.com/reaction/857776

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)-HCID 85083—
Reactant1-[5-fluoro-2-(1H-tetraazol-1-yl)phenyl]methanamineHCID 21866226—
ProductN-[5-fluoro-2-(1H-tetraazol-1-yl)benzyl]-L-prolinamideHCID 69655868—

Reaction Steps

The title compound was prepared essentially according to the procedures described in Example 26, Step B, starting from 1-[5-fluoro-2-(1H-tetraazol-1-yl)phenyl]methanamine and Boc-L-proline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07144899B2
Source datasetuspto-grants-2006_12
ORD IDord-7e75365b51b24483a806bd8ebbf6d59c
Source noteuspto-grants-2006_12