P-Anisidine → N-4-methoxyphenyl-N'-cyano-O-phenylisourea

Participants

Reaction Steps

A slurry of diphenyl cyancarbonimidate (1 g) in isopropanol (10 mL) was treated with 4-methoxyaniline (517 mg). After stirring at room temperature for a further 2.5 hours the reaction mixture was filtered. The insoluble material was washed with isopropanol to give the title compound (778 mg) as a white solid, which was used without further purification.

Provenance & Evidence