3-Methoxybenzenesulfonyl chloride → HCID 11758121, compound

HRID 858043Notes

Reaction equation

HRID 858043 reaction equation
[NH2:1][C:2]1[CH:31]=[CH:30][C:5]([CH2:6][C:7]2[NH:15][C:14]3[C:13](=[O:16])[N:12]([CH2:17][C:18]4[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=4[F:24])[C:11](=[O:25])[N:10]([CH2:26][CH:27]4[CH2:29][CH2:28]4)[C:9]=3[N:8]=2)=[CH:4][CH:3]=1.[CH3:32][O:33][C:34]1[CH:35]=[C:36]([S:40](Cl)(=[O:42])=[O:41])[CH:37]=[CH:38][CH:39]=1>>[CH:27]1([CH2:26][N:10]2[C:9]3[N:8]=[C:7]([CH2:6][C:5]4[CH:4]=[CH:3][C:2]([NH:1][S:40]([C:36]5[CH:37]=[CH:38][CH:39]=[C:34]([O:33][CH3:32])[CH:35]=5)(=[O:42])=[O:41])=[CH:31][CH:30]=4)[NH:15][C:14]=3[C:13](=[O:16])[N:12]([CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=3[F:24])[C:11]2=[O:25])[CH2:28][CH2:29]1

Participants

3

Reactant 2

HCID 27375043-Methoxybenzenesulfonyl chlorideHCID 218917373-Cyclopropylmethyl-8-[4-aminobenzyl]-1-(2-fluorobenzyl)-3,7-dihydro-purine-2,6-dione

Product 1

HCID 11758121HCID 11758121, compound

Procedure

Prepared from 8-(4-amino-benzyl)-3-cyclopropylmethyl-1-(2-fluoro-benzyl)-3,7-dihydro-purine-2,6-dione and 3-methoxy-benzenesulfonyl chloride. White solid; EI-HRMS m/e calculated for C30H28FN5O5S (M+) 589.1795, found 589.1801.

Sources & evidence

ORD record
ord-faddc77ad29947c2aba566c2dc0d66f7
Source dataset
uspto-grants-2006_12
Patent number
US07148229B2

Reaction notes

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