HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluorobenzenesulfonyl Chloride → N-{4-[3-Cyclopropylmethyl-1-(2-fluoro-benzyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl]-phenyl}-3-fluoro-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluorobenzenesulfonyl Chloride | HCID 2734258 | — |
| Reactant | 3-Cyclopropylmethyl-8-[4-aminobenzyl]-1-(2-fluorobenzyl)-3,7-dihydro-purine-2,6-dione | HCID 21891737 | — |
| Product | N-{4-[3-Cyclopropylmethyl-1-(2-fluoro-benzyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl]-phenyl}-3-fluoro-benzenesulfonamide | HCID 10031078 | — |
Reaction Steps
Prepared from 8-(4-amino-benzyl)-3-cyclopropylmethyl-1-(2-fluoro-benzyl)-3,7-dihydro-purine-2,6-dione and 3-fluoro-benzenesulfonyl chloride. Tan solid; EI-HRMS m/e calculated for C29H25F2N5O4S (M+) 577.1595, found 577.1599.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07148229B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-8f7e1ae327b74781a60faf9a4475fbdf |
| Source note | uspto-grants-2006_12 |