Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 858108Generated: October 25, 2026

2,5-Dimethoxybenzenesulfonyl chloride → N-{4-[3-Butyl-1-(2-fluoro-benzyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl]-phenyl}-2,5-dimethoxy-benzenesulfonamide

https://huagongshe.com/reaction/858108

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-Dimethoxybenzenesulfonyl chlorideHCID 137025—
Reactant1-(2-fluorobenzyl)-8-(4-aminobenzyl)-3-butyl-1H-purine-2,6(3H,7H)-dioneHCID 21891720—
ProductN-{4-[3-Butyl-1-(2-fluoro-benzyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl]-phenyl}-2,5-dimethoxy-benzenesulfonamideHCID 10100428—

Reaction Steps

Prepared from 8-(4-amino-benzyl)-3-butyl-1-(2-fluoro-benzyl)-3,7-dihydro-purine-2,6-dione and 2,5-dimethoxy-benzenesulfonyl chloride. Purity (ELSD, based on MW=621.7)=90%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07148229B2
Source datasetuspto-grants-2006_12
ORD IDord-5546a69e9313487db200def7a4226a46
Source noteuspto-grants-2006_12