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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 858113Generated: October 27, 2026

2,6-Dichlorobenzenesulfonylchloride → N-{4-[3-Butyl-1-(2-fluoro-benzyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl]-phenyl}-2,6-dichloro-benzenesulfonamide

https://huagongshe.com/reaction/858113

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-DichlorobenzenesulfonylchlorideHCID 522183—
Reactant1-(2-fluorobenzyl)-8-(4-aminobenzyl)-3-butyl-1H-purine-2,6(3H,7H)-dioneHCID 21891720—
ProductN-{4-[3-Butyl-1-(2-fluoro-benzyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl]-phenyl}-2,6-dichloro-benzenesulfonamideHCID 10077734—

Reaction Steps

Prepared from 8-(4-amino-benzyl)-3-butyl-1-(2-fluoro-benzyl)-3,7-dihydro-purine-2,6-dione and 2,6-dichloro-benzenesulfonyl chloride. Purity (ELSD, based on MW=630.5)=80%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07148229B2
Source datasetuspto-grants-2006_12
ORD IDord-392b49483fa341878bd22b01103377bb
Source noteuspto-grants-2006_12