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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 858130Generated: October 25, 2026

2,4-Dichloro-5-methylbenzene-1-sulphonyl chloride → N-{4-[3-Butyl-1-(2-fluoro-benzyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl]-phenyl}-2,4-dichloro-5-methyl-benzenesulfonamide

https://huagongshe.com/reaction/858130

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-Dichloro-5-methylbenzene-1-sulphonyl chlorideHCID 119914—
Reactant1-(2-fluorobenzyl)-8-(4-aminobenzyl)-3-butyl-1H-purine-2,6(3H,7H)-dioneHCID 21891720—
ProductN-{4-[3-Butyl-1-(2-fluoro-benzyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl]-phenyl}-2,4-dichloro-5-methyl-benzenesulfonamideHCID 58762846—

Reaction Steps

Prepared from 8-(4-amino-benzyl)-3-butyl-1-(2-fluoro-benzyl)-3,7-dihydro-purine-2,6-dione and 2,4-dichloro-5-methyl-benzenesulfonyl chloride. Purity (ELSD, based on MW=644.6)=82%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07148229B2
Source datasetuspto-grants-2006_12
ORD IDord-e3c0ab4d424f47b4874e594213631b96
Source noteuspto-grants-2006_12