2,1,3-Benzothiadiazole, 4-chlorosulfonyl- → HCID 10394089, compound

HRID 858136Notes

Reaction equation

HRID 858136 reaction equation
[NH2:1][C:2]1[CH:31]=[CH:30][C:5]([CH2:6][C:7]2[NH:15][C:14]3[C:13](=[O:16])[N:12]([CH2:17][C:18]4[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=4[F:24])[C:11](=[O:25])[N:10]([CH2:26][CH2:27][CH2:28][CH3:29])[C:9]=3[N:8]=2)=[CH:4][CH:3]=1.[N:32]1[S:36][N:35]=[C:34]2[C:37]([S:41](Cl)(=[O:43])=[O:42])=[CH:38][CH:39]=[CH:40][C:33]=12>>[CH2:26]([N:10]1[C:9]2[N:8]=[C:7]([CH2:6][C:5]3[CH:4]=[CH:3][C:2]([NH:1][S:41]([C:37]4[C:34]5=[N:35][S:36][N:32]=[C:33]5[CH:40]=[CH:39][CH:38]=4)(=[O:43])=[O:42])=[CH:31][CH:30]=3)[NH:15][C:14]=2[C:13](=[O:16])[N:12]([CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[F:24])[C:11]1=[O:25])[CH2:27][CH2:28][CH3:29]

Participants

3

Reactant 2

HCID 27354592,1,3-Benzothiadiazole, 4-chlorosulfonyl-HCID 218917201-(2-fluorobenzyl)-8-(4-aminobenzyl)-3-butyl-1H-purine-2,6(3H,7H)-dione

Product 1

HCID 10394089HCID 10394089, compound

Procedure

Prepared from 8-(4-amino-benzyl)-3-butyl-1-(2-fluoro-benzyl)-3,7-dihydro-purine-2,6-dione and benzo[1,2,5]thiadiazole-4-sulfonyl chloride. Purity (ELSD, based on MW=619.7)=80%.

Sources & evidence

ORD record
ord-e4a44a36fcb14c988c0cd2398e0e4566
Source dataset
uspto-grants-2006_12
Patent number
US07148229B2

Reaction notes

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