3-Methoxy-2-nitrobenzaldehyde → 3-Hydroxy-2-nitrobenzaldehyde

Participants

Reaction Conditions

Reaction Steps

3.62 g of 3-methoxy-2-nitrobenzaldehyde was dissolved in 80 ml of methylene chloride and a boron tribromide-methylene chloride solution (15.03 g of boron tribromide, 40 ml of methylene chloride) was added dropwise under ice cooling, followed by stirring at 0° C. for one hour. The reaction solution was poured into ice, extracted with chloroform, dried and then concentrated to obtain 3.32 g of the desired compound.

Provenance & Evidence