Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 8582생성일: 2026년 10월 25일
1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide → HCID 178419070, 화합물
https://huagongshe.com/reaction/8582
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide | HCID 11403986 | — |
| 반응물 | Diethyl 2-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)malonate | HCID 21983519 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | HCID 178419070 | HCID 178419070 | — |
반응 단계
0.50 g (1.11 mmol) of 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide (example I, step 5) are suspended in 40 ml of toluene. Then 1.40 g (5.16 mmol) of diethyl 2-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)malonate from step 5 are added. The mixture is stirred at 140° C. overnight. The solid is then filtered off with suction, washed with diethyl ether dried in vacuo.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US07091198B1 |
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| 출처 데이터셋 | uspto-grants-2006_08 |
|---|
| ORD ID | ord-c66547f1e8ed497f9aeea1ac5fc81abd |
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| 출처 메모 | uspto-grants-2006_08 |
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