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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 858224Generated: October 26, 2026

4-Chloro-2,5-dimethoxyaniline → N-(4-chloro-2,5-dimethoxyphenyl)-3-fluoro-4-methoxybenzamide

https://huagongshe.com/reaction/858224

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-2,5-dimethoxyanilineHCID 22833—
Reactant3-Fluoro-4-methoxybenzoic acidHCID 2733401—
ProductN-(4-chloro-2,5-dimethoxyphenyl)-3-fluoro-4-methoxybenzamideHCID 8409357—

Reaction Steps

The title compound was prepared in substantially the same manner as described in Example 1, step a, from 4-chloro-2,5-dimethoxyaniline, and 3-fluoro-4-methoxybenzoic acid and was obtained as a white solid, m.p. 197–199° C.; MS m/e 340 (M+H)+. Analysis for: C16H15ClFNO4 Calc'd: C, 56.56; H, 4.45; N, 4.12. Found: C, 56.33; H, 4.35; N, 4.05.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07148247B2
Source datasetuspto-grants-2006_12
ORD IDord-34d77f82e27b4d52a91b7fb158aa4e2b
Source noteuspto-grants-2006_12