3-Fluoro-4-methoxybenzoic acid → HCID 135443301, compound

HRID 858227Notes

Reaction equation

HRID 858227 reaction equation
[Br:1][C:2]1[C:8]([O:9]C)=[CH:7][C:5]([NH2:6])=[C:4]([O:11][CH3:12])[CH:3]=1.[F:13][C:14]1[CH:15]=[C:16]([CH:20]=[CH:21][C:22]=1[O:23]C)C(O)=O>>[Br:1][C:2]1[C:8]([OH:9])=[CH:7][C:5]2[N:6]=[C:12]([C:16]3[CH:20]=[CH:21][C:22]([OH:23])=[C:14]([F:13])[CH:15]=3)[O:11][C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 27334013-Fluoro-4-methoxybenzoic acidHCID 164901364-Bromo-2,5-dimethoxyaniline

Product 1

HCID 135443301HCID 135443301, compound

Procedure

The title compound was prepared in substantially the same manner as described in Example 16, from 4-bromo-2,5-dimethoxyaniline, and 3-fluoro-4-methoxybenzoic acid and was obtained as a white solid, m.p. 224–226° C.; MS m/e 322 (M−H)+.

Workup

  1. customwas obtained as a white solid, m.p. 224–226° C.

Sources & evidence

ORD record
ord-3833b69be985456b9ee56abc0413acac
Source dataset
uspto-grants-2006_12
Patent number
US07148247B2

Reaction notes

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