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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 858255Generated: October 26, 2026

4-Methoxy-3-(trifluoromethyl)benzoyl chloride → 2-Bromo-4-methoxy-6-{[4-methoxy-3-(trifluoromethyl)benzoyl]amino}phenyl 4-methoxy-3-(trifluoromethyl)benzoate

https://huagongshe.com/reaction/858255

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxy-3-(trifluoromethyl)benzoyl chlorideHCID 2775298—
Reactant2-Amino-6-Bromo-4-MethoxyphenolHCID 11171982—
Product2-Bromo-4-methoxy-6-{[4-methoxy-3-(trifluoromethyl)benzoyl]amino}phenyl 4-methoxy-3-(trifluoromethyl)benzoateHCID 22669162—

Reaction Steps

The title compound was prepared in substantially the same manner as described in Example 20, Step c, from 2-amino-6-bromo-4-methoxyphenol and 4-methoxy-3-trifluoromethyl benzoyl chloride. The product was obtained as an off-white solid, m.p. 205–208° C.; MS m/e 622 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07148247B2
Source datasetuspto-grants-2006_12
ORD IDord-f39899d1ae544f049ac6f1d75eba8ac2
Source noteuspto-grants-2006_12