N,N-Dimethylethylenediamine → Sulfanilamide, N(sup 1)-(2-(dimethylamino)ethyl)-

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Reaction Steps

5.26 g sulphanilic acid fluoride and 16.5 ml of N,N-dimethyl-ethylenediamine are stirred for 4 hours at 100° C., then dissolved in ethyl acetate and extracted three times with saline solution. The residue obtained by evaporation of the organic phase is crystallised from diethyl ether and dried at 60° C.

Provenance & Evidence