Beta-Alanine → HCID 2304977, compound

Participants

Reaction Steps

4-carboxyphthalic anhydride (1.0 g, 0.0052 mol) and β-alanine (0.46, 0.0052 mol) were refluxed as above for 7 hours. Crystallisation of the product from EtOH yielded 1.37 g (78%) of 101 as a white solid: mp=240–242° C.; Rf 0.77 (A): Rf 0.67 (B): Rf 0.33 (D): 1H NMR (DMSO-d6); MS m/z (rel intensity) 263 (14), 262 (100); IR (cm−1): 2800–3250 (OH), 3150 (C═CH), 2671 (C—H), 1777 (C═O), 1725 (C═O), 1705 (C═O), 1620 (C═C), 1452 (C═C), 1385(C—O), 1226 (C—O), 731 (C═CH). MS m/z (rel intensity) 263 (14), 262 (100).

Provenance & Evidence