4-Aminobenzoic Acid → HCID 728460, compound

Participants

Reaction Steps

4-carboxyphthalic anhydride (1.0 g, 0.0052 mol) and p-aminobenzoic acid (0.714 g, 0.0052 mol) were refluxed as above overnight. A clean product from the mother liquor fraction was not obtained. Crystallisation of the precipitated product from MeOH/H2O yielded 0.88 g (55%) of 105 as a white solid: mp=377–379° C.; Rf 0.90 (A): Rf 0.76 (B): Rf 0.46 (D): IR (cm−1): 2750–3200 (OH), 3077 (C═CH), 2652 (C—H), 1777 (C═O), 1731 (C═O), 1699 (C═O), 1604 (C═C), 1512 (C═C), 1485 (C═C), 1428 (C═C), 1376 (C—O), 1310 (C—O), 1092 (C—O), 723 (C═CH); MS m/z (rel intensity) 311 (23), 310 (100).

Provenance & Evidence