HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(6-Chloro-5-nitropyridin-3-yl)ethanone → 1-[6-({4-[2-Hydroxypropyl]phenyl}amino)-5-nitro-3-pyridinyl]ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(6-Chloro-5-nitropyridin-3-yl)ethanone | HCID 14762705 | — |
| Reactant | 1-(4-Aminophenyl)-2-propanol | HCID 21875672 | — |
| Product | 1-[6-({4-[2-Hydroxypropyl]phenyl}amino)-5-nitro-3-pyridinyl]ethanone | HCID 21875957 | — |
Reaction Steps
The title compound was prepared according to the procedure described in step 1 of Example 162 from 1-(6-chloro-5-nitro-3-pyridinyl)ethanone (Paul, B. et al. J. Med. Chem., 1990, 33, 2231–2239.) and 1-(4-aminophenyl)-2-propanol (step 1 of Example 6).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07148234B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-a31f8e1b88f44e9491189a0b49a3e452 |
| Source note | uspto-grants-2006_12 |