Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(6-Chloro-5-nitropyridin-3-yl)ethanone → 1-[6-({4-[(2S)-2-hydroxypropyl]phenyl}amino)-5-nitro-3-pyridinyl]ethanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(6-Chloro-5-nitropyridin-3-yl)ethanone | HCID 14762705 | — |
| 반응물 | (S)-1-(4-aminophenyl)propan-2-ol | HCID 67099494 | — |
| 생성물 | 1-[6-({4-[(2S)-2-hydroxypropyl]phenyl}amino)-5-nitro-3-pyridinyl]ethanone | HCID 67099421 | — |
반응 단계
The title compound was prepared according to the procedure described in step 1 of Example 162 from 1-(6-chloro-5-nitro-3-pyridinyl)ethanone (Paul, B. et al. J. Med. Chem., 1990, 33, 2231–2239.) and (2S)-1-(4-aminophenyl)-2-propanol (step 2 of Example 248).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07148234B2 |
| 출처 데이터셋 | uspto-grants-2006_12 |
| ORD ID | ord-0fdbb9d69b4d467cb4983c887172f7ab |
| 출처 메모 | uspto-grants-2006_12 |